Duke Precision Medicine Forum: Sarah Heston, MD and Nathan Bihlmeyer, PhD

May 26, 2022 - 12:00pm to 1:00pm

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Sarah Heston, MD
Second-year Postdoctoral Fellow, Genomic Medicine Research Trainee (T32)
Fellow, Advanced Research Training Program, Pediatric Infectious Diseases
Duke University School of Medicine
"Effects of Antibiotic Exposures on the Gut Resistome after Hematopoietic Stem Cell Transplantation in Children"

Sarah M. Heston, MD, is currently a fellow in the Advanced Research Training Program in Pediatric Infectious Diseases. Her research focuses on the ability of the gut metagenome to predict clinical outcomes after hematopoietic stem cell transplantation (HSCT) in children. Her current work is determining the effect of antibiotic exposures on the collection of antibiotic resistance genes within the gut metagenome, collectively referred to as the "resistome." After completion of her fellowship, Sarah will stay at Duke as an Assistant Professor in Pediatric Infectious Diseases. Her future work will determine the gut metagenome's role in the development of mucosal barrier injury bloodstream infections after HSCT.

Nathan Bihlmeyer, PhD
Second-year Postdoctoral Fellow, Genomic Medicine Research Trainee (T32)
Duke Molecular Physiology Institute
Duke University School of Medicine
"Pediatrics and proteins: Unique biology of children undergoing obesity intervention and association to cardiovascular health"

Nathan Bihlmeyer, PhD, is currently a computational genetics post-doc fellow in Svati Shah's lab at Duke studying molecular mechanisms of pediatric and adult obesity, with a focus on microbiome-mediated metabolic pathways. The design of the primary study involves using multi-omics (metabolomics, proteomics, microbiome metagenomics, and lipidomics) before and after a multi-factorial diet and exercise intervention in children with obesity from two cohorts.

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