PROMISE Trial

Research Aims

PROMISE (Prospective Multicenter Imaging Study for Evaluation of Chest Pain) is a prospective, randomized trial comparing two diagnostic testing strategies for coronary artery disease (CAD) - coronary computed tomographic angiography (CTA) relative to standard-of-care functional testing.

Experimental Design

Subjects: 7867

Timepoints: variable

Sample types:

  • plasma:20536
  • serum:34492
  • whole blood, EDTA:2824
  • PAXgene blood RNA:8069
  • RNA total:4426
  • RNA:4017
  • packed blood cells:2873

Datasets

Clinical: CRF/clinical, demographics, labs, meds, comorbidities, outcomes, anatomic imaging

Molecular: plasma proteomics, plasma metabolomics, blood RNAseq

Publications