Recent News
National Human Genome Research Institute offers funding opportunities
Funding supports research, training, and career development opportunities to accelerate scientific and medical breakthroughs that improve human health.
How you can help scientists better understand COVID variants through wearable devices
Duke researchers, including CAGPM's Chris Woods, Ryan Shaw, and Jessilyn Dunn, are investigating whether data from your smartphone and smartwatch can help determine if you have COVID-19 and how severe the infection could get. Their work has the potential to help avoid future pandemics, but they need more participants to enroll.
Vigilance needed for COVID to move from pandemic to endemic, experts say
CAGPM's Christopher Woods among Duke experts offer a bracing word of caution: The virus will remain dangerous and require a stronger global vaccination effort, and people should remain vigilant, safe and responsible
Tsalik featured in Duke's Year in Science Roundup
Ephraim Tsalik and Duke researchers are finding the testing tool could help clinicians know when to correctly prescribe antibiotics
Apply Now for a 2022-2023 Bass Connections Project Team
Applications are due by Feb. 11, 2022
Funding Opportunity: Duke School of Medicine Biomedical PhD Student Research Pilot Grants
The deadline for applications is Feb. 15, 2022
Events
Medicine Grand Rounds: Michael J. Pencina and Armando Bedoya
January 28, 2022 - 12:00pm
Duke Research Week 2022
January 31, 2022 (All day)
IHCC Educational Webinar Series
January 31, 2022 - 2:00pm
Duke Research & Innovation 2022 Daubechies Lecture: Bonnie L. Bassler, PhD
February 2, 2022 - 11:30am
Genomic & Precision Medicine Forum Series: Liz Cirulli, PhD
February 10, 2022 - 12:00pm
SOM Faculty Development Resources
February 14, 2022 - 10:00am
SOM Genomic Seminar Series: Eric Green, Director of National Human Genome Research Institute
February 21, 2022 - 4:00pm
Genomic & Precision Medicine Forum Series: William E. Kraus, MD
February 24, 2022 - 12:00pm
New Funding
Micah McClain, MD, has received an award from Biomeme, Inc. for a project entitled "Biomeme Franklin ISP SARS-CoV-2 + Influenza Multiplexed RT-PCR Test Point of Care Study including Saletto Oral Fluid Collection."
Lori Orlando, MD, MHS, has received an award (1R01-HG011794-01) from the National Institutes of Health for a project entitled "Deploying a genomic-medicine risk assessment model for diverse primary care populations and settings."
Geoffrey Ginsburg, MD, PhD has received an award (5U01-HG010225-04S1) from the National Institutes of Health for a project entitled "The IGNITE II CC: Engagement, Coordination, Demonstration, and Dissemination."
Ephraim Tsalik, MD, PhD, has received an award (W81XWH2110741-PR201197) from the Department of Defense for a project entitled "Rapid, point-of-care, host gene expression test for presymptomatic viral infection and to distinguish bacterial from viral illness."
Christopher Woods, MD, received a sub-award (W911QY-19-9-0006) through the Henry M. Jackson Foundation for a project entitled "Prophylaxis and Treatment of COVID19 Adaptive Platform Trial (PROTECT-APT)." (June 2021, Sponsored Research)
Featured Publications
A comparison of host response strategies to distinguish bacterial and viral infection
Ricardo Henao, Tom Burke, Emily Ko, Micah McClain, Christopher Woods, Ephraim Tsalik and co-authors compare three host response strategies to distinguish bacterial and viral etiologies of acute respiratory illness (PLoS One)
A Gene Expression Signature Reflective of Exposure to Antiplatelet Therapy is Associated with Bleeding
Deepak Voora, Rachel Myers, Ilya Zhannikov, and team find biosignatures composed of gene expression data hold promise for personalized antiplatelet therapy in conjunction with current guidelines and risk scores. (AHA Journals/Circulation)
Artificial intelligence enables comprehensive genome interpretation and nomination of candidate diagnoses for rare genetic diseases
Jeanette McCarthy and co-authors discuss diagnostic performance of Fabric GEM, a new, AI-based, clinical decision support tool for expediting genome interpretation. (Genome Medicine, part of Springer Nature)
Demographic Imbalances Resulting from Bring-Your-Own-Device Study Design
Ryan Shaw, Christopher Woods, Jessilyn Dunn and team investigate demographic imbalances discovered in existing BYOD studies and propose a Demographic Improvement Guideline to offset these imbalances (JMIR Publications)
Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information
Douglas E. Williamson and co-authors investigate a quantitative approach to PTSD phenotype measurement and incorporation of lifetime trauma exposure (LTE) information to enhance the discovery power of PTSD genome-wide association studies (Biological Psychiatry)
Experience and Perceptions of a Family Health History Risk Assessment Tool among Multi-Ethnic Asian Breast Cancer Patients
Ryanne Wu, Lori Orlando, and team explore perceptions of the value of knowing one’s family health history (FHH)-based risk and potential implementation of a FHH tool (Journal of Personalized Medicine)
Core Resources
Diagnostics Development Laboratory
The laboratory brings together expertise in molecular microbiology with genome sciences to develop next-generation diagnostic tests.
BioBank
We support biobanking activities including IRB, sample collection, processing, storage, bar-coded chain of custody and e-inventory management.
Data Science and Analytics
We provide support for data management and integration, informatics, and statistical analyses on complex ‘-omics’ and clinical datasets.