Recent News
New Metastatic Breast Cancer Drug Trial Launches
P. Kelly Marcom and Dorothy Sipkins launched a proof-of-concept clinical trial of a new drug for hormone receptor positive breast cancer patients whose disease has spread to the bone.
Smart Toilet Saves Vital Health Data from Getting Flushed
Co-led by Geoff Ginsburg, the Smart Toilet Bass Connections team has been hard at work developing prototypes of a "Smart Toilet," which would enable the hands-free collection of waste that can be used for early disease detection and to test and monitor for infectious diseases.
Precision Medicine in Primary Care: Bespoke. Genetic and Genomic. And Maybe Not Ready.
With genomic sequencing on the rise and patients having more say about their treatment, two hot areas—predictive genetic testing and pharmacogenomics—promise to extend “personalized” medicine beyond cancer care. But will this precision improve outcomes and pay for itself? Susanne Haga weighs in.
A Crystal Ball For the Decade Ahead
From robots in the home to advanced medicine via an app, Duke faculty offer ideas for the world of 2030. Geoff Ginsburg gave his insights on what he thinks precision medicine will look like in a decade.
Deepak Voora to Present at PMWC 2020
CAGPM faculty member Deepak Voora will present at the 2020 Precision Medicine World Conference (PMWC) in Silicon Valley.
Bacterial, Viral, or Neither? Host Response Test Has Answers
Predigen, a Duke spin-out company, is putting the finishing touches on a host response bacterial-viral test entering the final leg of the Antimicrobial Resistance Diagnostic Challenge.
Events
Webinar Series- Advancing Precision Health: The Opportunity that is Pharmacogenomics
July 2, 2019 - 8:00am
Grow and Advance as PoPs, Lecturers, and Research Faculty
February 27, 2020 - 12:00pm
Perkins Library 217, Kornman Assembly Room
Seeking Ethical Solutions to New (and old) Problems
March 3, 2020 - 5:30pm
Great Hall, Trent Semans Center for Health Education
New Funding
Lori Orlando, along with a team at Vanderbilt, was awarded a NIH Moonshot grant focused on boosting hereditary cancer identification. The team will use MeTree to collect and analyze family health history.
The Enabling Precision Health and Medicine Bass Connections team, led by Susanne Haga has been renewed for the 2019-2020 school year.
A new Bass Connections project, the Smart Toilet: A disruptive technology to improve health and wellness, led by Geoff Ginsburg, has been funded for the 2019-2020 school year.
Ephraim Tsalik is one of five finalists for the Antimicrobial Resistance Diagnostic Challenge through NIH. He will receive a grant to further develop his prototype and supply it for testing to two CLIA-certified independent laboratories.
Seen & Heard
Doraiswamy Hosts George Church at Genomic and Precision Medicine Forum
CAGPM affiliated faculty member Murali Doraiswamy, M.D., hosted George Church, Ph.D., at the Genomic and Precision Medicine Weekly Forum.
Featured Publications
CAGPMers discuss importance of family health history
CAGPM faculty published a paper in The Lancet discussing family health history and how it is underused for actionable risk assessment in patients.
CAGPMers validate host response test to distinguish bacterial and viral respiratory infection
CAGPM faculty and staff members validate a microarray-derived host response signature and explore performance in microbiology-negative and coinfection cases.
Ginsburg evaluates the opportunities, resources, and techniques for implementing genomics in clinical care
Geoff Ginsburg and team review the major technologies used in genomic medicine, discuss approaches to interpret genomic sequence variants, identify publicly available tools for genomic test interpretation, and address barriers to using genomic information in routine practice.
Haga discusses pharmacogenomic testing in pedatrics
In a new review, Susanne Haga provides background on the use of PGx testing in children as well as mothers and discusses the challenges, benefits, and the ethical, legal and social implications of providing PGx testing to children.
Haga, Myers and Orlando assess awareness of family health history (FHH) in young adults
Susanne Haga, Rachel Myers and Lori Orlando assessed young adults' attitudes and knowledge about FHH to understand the barriers to FHH-based risk assessment in young adults. The team also developed and evaluated educational resources designed specifically for young adults.
Lori Orlando and team build evidence and measure clinical outcomes for genomic medicine
Orlando was co-author of a paper focusing on the international efforts to build evidence for the optimal return of disease risk genetic variants and use of this data within routine clinical care.
Core Resources
Diagnostics Development Laboratory
The laboratory brings together expertise in molecular microbiology with genome sciences to develop next-generation diagnostic tests.
BioBank
We support biobanking activities including IRB, sample collection, processing, storage, bar-coded chain of custody and e-inventory management.
Data Science and Analytics
We provide support for data management and integration, informatics, and statistical analyses on complex ‘-omics’ and clinical datasets.