Recent News
Join the NHGRI in Healthcare Professionals' Genomics Education Week
The National Human Genome Research Institute and its partners are organizing a social media campaign from June 6-10, 2022, that focuses on healthcare provider genomics education.
2022 Summer Scholars Officially Kicks Off
The Duke Center for Genomic and Computational Biology (GCB) and the Center for Precision Medicine has partnered once again with North Carolina Central University (NCCU) for the Summer Scholars Program in Genome Sciences and Medicine, welcoming students to Durham, North Carolina
Ryanne Wu on her path to precision medicine
Wu is an internal medicine physician and health services researcher at Duke with an emphasis on precision medicine.
Snyderman Scholars program kicks off at Duke
There are two Snyderman Scholars this summer, Jiung (Peter) Nam and Paul Tongji Kim.
A Day of Renewal: Duke's Moments to Movement
Join your fellow team members to renew your own well-being and our mutual commitment to Moments to Movement during one of four virtual sessions offered on May 25th.
Reflections from the upcoming T32 graduates
Sarah Heston, MD, and Nathan Bihlmeyer, PhD, will graduate the Post-Doctoral Training in Genomic Medicine Research Program at the end of June.
Events
4th University of Minnesota Biennial Pharmacogenomics Conference
September 21, 2022 (All day)
New Funding
Christopher Woods, MD, has received a sub-award (W911QY-19-9-0006) through the Henry M. Jackson Foundation for a project entitled "Prophylaxis and Treatment of COVID19 - Adaptive Platform Trial" (PROTECT-APT)
Micah McClain, MD, has received an award from Biomeme, Inc. for a project entitled "Biomeme Franklin ISP SARS-CoV-2 + Influenza Multiplexed RT-PCR Test Point of Care Study including Saletto Oral Fluid Collection."
Lori Orlando, MD, MHS, has received an award (1R01-HG011794-01) from the National Institutes of Health for a project entitled "Deploying a genomic-medicine risk assessment model for diverse primary care populations and settings."
Ephraim Tsalik, MD, PhD, has received an award (W81XWH2110741-PR201197) from the Department of Defense for a project entitled "Rapid, point-of-care, host gene expression test for presymptomatic viral infection and to distinguish bacterial from viral illness."
Christopher Woods, MD, received a sub-award (W911QY-19-9-0006) through the Henry M. Jackson Foundation for a project entitled "Prophylaxis and Treatment of COVID19 Adaptive Platform Trial (PROTECT-APT)." (June 2021, Sponsored Research)
Featured Publications
A comparison of host response strategies to distinguish bacterial and viral infection
Ricardo Henao, Tom Burke, Emily Ko, Micah McClain, Christopher Woods, Ephraim Tsalik and co-authors compare three host response strategies to distinguish bacterial and viral etiologies of acute respiratory illness (PLoS One)
A Gene Expression Signature Reflective of Exposure to Antiplatelet Therapy is Associated with Bleeding
Deepak Voora, Rachel Myers, Ilya Zhannikov, and team find biosignatures composed of gene expression data hold promise for personalized antiplatelet therapy in conjunction with current guidelines and risk scores. (AHA Journals/Circulation)
Artificial intelligence enables comprehensive genome interpretation and nomination of candidate diagnoses for rare genetic diseases
Jeanette McCarthy and co-authors discuss diagnostic performance of Fabric GEM, a new, AI-based, clinical decision support tool for expediting genome interpretation. (Genome Medicine, part of Springer Nature)
Demographic Imbalances Resulting from Bring-Your-Own-Device Study Design
Ryan Shaw, Christopher Woods, Jessilyn Dunn and team investigate demographic imbalances discovered in existing BYOD studies and propose a Demographic Improvement Guideline to offset these imbalances (JMIR Publications)
Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information
Douglas E. Williamson and co-authors investigate a quantitative approach to PTSD phenotype measurement and incorporation of lifetime trauma exposure (LTE) information to enhance the discovery power of PTSD genome-wide association studies (Biological Psychiatry)
Experience and Perceptions of a Family Health History Risk Assessment Tool among Multi-Ethnic Asian Breast Cancer Patients
Ryanne Wu, Lori Orlando, and team explore perceptions of the value of knowing one’s family health history (FHH)-based risk and potential implementation of a FHH tool (Journal of Personalized Medicine)
Core Resources
Diagnostics Development Laboratory
The laboratory brings together expertise in molecular microbiology with genome sciences to develop next-generation diagnostic tests.
BioBank
We support biobanking activities including IRB, sample collection, processing, storage, bar-coded chain of custody and e-inventory management.
Data Science and Analytics
We provide support for data management and integration, informatics, and statistical analyses on complex ‘-omics’ and clinical datasets.