Recent News
New Books by Duke Authors Capture the Imagination this Spring
"The Book of Genes and Genomes", authored by Susanne Haga, PhD, featured in Duke Today
Revised Duke Health Social Media Policy
A new, revised Duke Health Social Media Policy has been finalized. Check out what's new.
Call for Applications: Joint Postdoctoral Fellowship in Clinical Ethics and the ELSI of Precision Medicine
The application deadline is May 31, 2022
Call for applications - Microbiome/Metagenome data analysis workshop on May 11
If you are interested in attending the workshop, please complete the questionnaire by email by 5 pm on May 4, 2022.
April 25 is National DNA Day
National DNA Day is a unique day when students, teachers, and the public can learn more about genetics and genomics. The day commemorates the completion of the Human Genome Project in 2003 and the discovery of DNA's double helix in 1953.
Orlando to present during Public Health Genetics Week
Public Health Genetics Week will take place May 23-27, 2022 and virtual events are free and open to the public
Events
16th Annual Personalized Medicine Conference
May 19, 2022 - 12:00pm
Duke Margolis Center for Health Policy: FDA Translational Sciences Virtual Meeting
May 24, 2022 (All day)
National Human Genome Research Institute Roundtable
May 25, 2022 - 1:00pm
Duke Precision Medicine Forum: Sarah Heston, MD and Nathan Bihlmeyer, PhD
May 26, 2022 - 12:00pm
4th University of Minnesota Biennial Pharmacogenomics Conference
September 21, 2022 (All day)
New Funding
Christopher Woods, MD, has received a sub-award (W911QY-19-9-0006) through the Henry M. Jackson Foundation for a project entitled "Prophylaxis and Treatment of COVID19 - Adaptive Platform Trial" (PROTECT-APT)
Micah McClain, MD, has received an award from Biomeme, Inc. for a project entitled "Biomeme Franklin ISP SARS-CoV-2 + Influenza Multiplexed RT-PCR Test Point of Care Study including Saletto Oral Fluid Collection."
Lori Orlando, MD, MHS, has received an award (1R01-HG011794-01) from the National Institutes of Health for a project entitled "Deploying a genomic-medicine risk assessment model for diverse primary care populations and settings."
Ephraim Tsalik, MD, PhD, has received an award (W81XWH2110741-PR201197) from the Department of Defense for a project entitled "Rapid, point-of-care, host gene expression test for presymptomatic viral infection and to distinguish bacterial from viral illness."
Christopher Woods, MD, received a sub-award (W911QY-19-9-0006) through the Henry M. Jackson Foundation for a project entitled "Prophylaxis and Treatment of COVID19 Adaptive Platform Trial (PROTECT-APT)." (June 2021, Sponsored Research)
Featured Publications
A comparison of host response strategies to distinguish bacterial and viral infection
Ricardo Henao, Tom Burke, Emily Ko, Micah McClain, Christopher Woods, Ephraim Tsalik and co-authors compare three host response strategies to distinguish bacterial and viral etiologies of acute respiratory illness (PLoS One)
A Gene Expression Signature Reflective of Exposure to Antiplatelet Therapy is Associated with Bleeding
Deepak Voora, Rachel Myers, Ilya Zhannikov, and team find biosignatures composed of gene expression data hold promise for personalized antiplatelet therapy in conjunction with current guidelines and risk scores. (AHA Journals/Circulation)
Artificial intelligence enables comprehensive genome interpretation and nomination of candidate diagnoses for rare genetic diseases
Jeanette McCarthy and co-authors discuss diagnostic performance of Fabric GEM, a new, AI-based, clinical decision support tool for expediting genome interpretation. (Genome Medicine, part of Springer Nature)
Demographic Imbalances Resulting from Bring-Your-Own-Device Study Design
Ryan Shaw, Christopher Woods, Jessilyn Dunn and team investigate demographic imbalances discovered in existing BYOD studies and propose a Demographic Improvement Guideline to offset these imbalances (JMIR Publications)
Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information
Douglas E. Williamson and co-authors investigate a quantitative approach to PTSD phenotype measurement and incorporation of lifetime trauma exposure (LTE) information to enhance the discovery power of PTSD genome-wide association studies (Biological Psychiatry)
Experience and Perceptions of a Family Health History Risk Assessment Tool among Multi-Ethnic Asian Breast Cancer Patients
Ryanne Wu, Lori Orlando, and team explore perceptions of the value of knowing one’s family health history (FHH)-based risk and potential implementation of a FHH tool (Journal of Personalized Medicine)
Core Resources
Diagnostics Development Laboratory
The laboratory brings together expertise in molecular microbiology with genome sciences to develop next-generation diagnostic tests.
BioBank
We support biobanking activities including IRB, sample collection, processing, storage, bar-coded chain of custody and e-inventory management.
Data Science and Analytics
We provide support for data management and integration, informatics, and statistical analyses on complex ‘-omics’ and clinical datasets.