Center Biobank

researcher inputting sample data into computer

Recognizing the critical importance of high-quality, well-annotated biospecimens for researching the molecular underpinnings of health and disease, we have established a standardized, regulatory-compliant, and genetic privacy protected institutional repository for fluid and tissue biospecimens, allowing investigators to reduce costs, redundancies, and risks associated with alternative to reduce costs, redundancies, and risks associated with alternative bio-banking strategies. The facility integrates clinical research programs with molecular profiling technologies, enabling large-scale genomics and proteomics research programs that will inform and drive the development of new generations of targeted diagnostics and therapies. 

Our facility provides support of clinical research studies involving specimen collections, annotation, inventory management, and sample analysis. 

Facilities and Capabilities

Biobanking activities are centralized in the GAD3 Laboratory space in CIEMAS building. This central location serves as the sample receipt and accessioning area, provides dedicated sample processing/QC workspace, and offers short-term specimen storage in an ultralow freezer. Long term storage is provided on campus at a Duke Hospital South location and at an off-site facility in Research Triangle Park. Storage facilities are restricted to authorized personnel only and provide appropriate environmental controls. Each freezer unit has 24-hour wireless temperature monitoring, an active notification system and an emergency generator for back-up power. The biobank employs LabVantage™ to support all aspects of sample management including data entry, barcode-based chain-of-custody tracking and inventory management, specimen annotation, flexible query and data reporting while providing access controls ensuring data security and integrity.

The key capabilities include 

  • SOP-guided sample processing, handling and storage to support clinical genomics research
  • Secure, monitored, ultra-low temperature specimen storage with appropriate environmental controls and power redundancy
  • Web-based informatics for sample annotation, barcode-based chain of custody tracking, inventory management and data query

 

 

 

Biospecimen Resources:

Over 340,000 high quality, well-annotated biospecimens from 10,000 research participants enrolled in a clinical genomic studies - many with longitudinal sampling, clinical annotation and orthogonal molecular data. May be available for collaborative research opportunities.

Descriptions of Biospecimen Research Collections

Contact

For questions regarding the BioBank or our biospecimens, contact Tom Burke (thomas.burke@duke.edu).