Risk Assessment

Health assessment tools can help you and your provider better understand and quantify your risk for specific diseases and establish goals and strategies for better health. Disease risk assessments use an individual’s personal, genetic and environmental information to determine a quantitative or qualitative value of risk for developing specific diseases. Many of these tools are designed for use by health professionals. If you are not a health professional, you are encouraged to discuss the results and your personal risk of disease with your doctor.

Projects

MeTree Family History Tool

The Duke Center for Applied Genomics and Precision Medicine has developed a risk assessment tool called MeTree. This web-based, patient-facing risk assessment tool collects personal health information and family health history. Algorithms are run based on current clinical guidelines used by primary care physicians to create patient- and provider-directed risk assessment reports. MeTree also creates a three-generation pedigree and tabular version of the family health history. Implementation of MeTree is currently being studied in an ongoing NIH-funded trial as part of the IGNITE network to understand how to best implement IT tools like MeTree in various settings and with diverse populations. Learn more

For more information, contact: Lori Orlando, MD

Type 2 Diabetes Genetic Risk Testing in Primary Care

Risk assessments based on traditional risk factors for type 2 diabetes (T2D) have only limited success in identifying at-risk patients and motivating them to modify their lifestyles for prevention. Genetic advances have identified markers for T2D, which, when combined with traditional risk factors, may improve the clinical utility of risk assessment, particularly as it relates to motivating healthier diet and exercise behaviors. The purpose of this study was to assess the clinical and personal utility of incorporating T2D genetic risk testing into comprehensive diabetes risk assessments performed in a primary care setting.

For more information, contact: Allison A. Vorderstrasse, DNSc, APRN

Genetic Risk Testing and Health Coaching for Type 2 Diabetes and Coronary Heart Disease

Military personnel are not exempt from increasing rates of overweight and obesity or the associated rising burden of coronary heart disease (CHD) and type 2 diabetes (T2D) seen in the U.S. population. Innovative and clinically feasible approaches to addressing these chronic disease risks are needed, particularly those that motivate and support sustainable, risk-reducing health behaviors. Risk assessment (global, genetic, etc.), historically based on clinical risk factors (e.g., blood pressure, cholesterol) alone, is a central aspect of preventive care. This study examines the clinical utility of genetic CHD and T2D risk information with and without concomitant behavioral intervention in promoting risk-reducing behaviors and improving clinical outcomes. The purpose of this four group (2X2) randomized controlled trial (RCT) is to determine whether incorporating multiple-marker genetic testing into risk counseling for CHD and T2D, coupled with a health coaching intervention will lead to greater changes in physical fitness, health behaviors, disease risk status and clinical outcomes in active-duty Air Force (ADAF) primary care patients at risk for CHD or T2D.

For more information, contact: Allison A. Vorderstrasse, DNSc, APRN

Resources